Cancer Archives - Purablis-Medicinal Tinctures with CBD, THCA and THC

Cancer Marijuana Studies and

Cancer Cannabis Research

09/27/2018

Author(s): Lesley A Smith, Fredric Azariah, Verna TC Lavender, Nicola S Stoner, Silvana Bettiol.

Conventional anti-cancer drugs do not always work for everyone, and can cause nausea and vomiting. Therefore, therapeutic THC-based drugs (Cannabis) have already been approved for use in some countries. View study

09/27/2018

Author(s): Simona Pisanti, Cristina Borselli, Olimpia Oliviero, Chiara Laezza, Patrizia Gazzero, and Maurizio Bifulco.

Anandamide is potentially involved in the control of cancer growth directed both to the proliferation of tumor cells and to the angiogenic stimulation of the vasculature. View study

09/27/2018

Author(s): G. Velasco; C. Sánchez and M. Guzmán.

There is a lot of evidence that shows how cannabinoids can reduce cancer tumors in animals. These findings already serve as the basis for the development of studies that analyze the therapeutic potential of cannabinoids to fight cancer. View study

09/27/2018

Author(s): CHENGZHI XIE, GUOXING LIU, JIEFENG LIU, ZHAO HUANG, FUSHENG WANG, XIAOHUA LEI, XIAOLONG WU, SHENGFU HUANG, DEWU ZHONG and XUNDI XU.

A study demonstrating that endogenous cannabinoid anandamide AEA inhibits the proliferation of cancer cells and induces cellular apoptosis, suggesting its therapeutic potential in the treatment of patients with human hepatocellular carcinoma. View study

09/27/2018

Author(s): ISMAEL GALVE-ROPERH, CRISTINA SÁNCHEZ , MARÍA LUISA CORTÉS , TERESA GÓMEZ DEL PULGAR , MARTA IZQUIERDO & MANUEL GUZMÁN.

THC (the main component of cannabis) induces apoptosis (cell death) of cancer cells in culture. Its intratumoral administration induced a considerable regression of malignant gliomas. View study

09/27/2018

Author(s): D. Vara , M. Salazar, N. Olea-Herrero, M. Guzmán, G. Velasco, and I Díaz-Laviada.

Findings that reveal the therapeutic potential of cannabinoids for the treatment of hepatocellular carcinoma, especially in advanced stages. View study

09/27/2018

Author(s): Nadine Freimuth, Robert Ramer, and Burkhard Hinz.

Cannabinoids may likewise affect cancer cell angiogenesis, migration, invasion, adhesion, and metastasization. View study

09/27/2018

Author(s): M. Guzmán, M.J. Duarte , C. Blázquez , J. Ravina, M.C. Rosa, I. Galve-Roperh , C. Sánchez , G. Velasco and L. González-Feria.

Due to its ability to inhibit tumor growth in animals, THC and other cannabinoids have been suggested as antitumor drugs. This is the first clinical study to test the application of THC in human patients with recurrent glioblastoma multiforme. The results demonstrate the safety profile of THC and its action on tumor cells, which establishes the basis for future trials. View study

09/27/2018

Author(s): Natalya M. Kogan, Cristina Blazquez, Luis ´ Alvarez, Ruth Gallily, Michael Schlesinger, ´ Manuel Guzman, and Raphael Mechoulam.

Cannabidiol hydroxyquinone (HU-331) has a great potential to become an antiangiogenic and anticancer drug. This study demonstrated that HU-331 was able to significantly inhibit angiogenesis at very low concentrations, in addition to significantly decreasing the total area occupied by the vessels in the treated tumors. View study

09/27/2018

Author(s): Alessia Ligresti, Aniello Schiano Moriello, Katarzyna Starowicz, Isabel Matias, Simona Pisanti, Luciano De Petrocellis, Chiara Laezza, Giuseppe Portella, Maurizio Bifulco, and Vincenzo Di Marzo.

A comparison of antitumor properties of different cannabinoids. The results obtained show that cannabidiol is the most potent inhibitor of the growth of cancer cells. View study

09/27/2018

Author(s): M. Guzmán, M.J. Duarte , C. Blázquez , J. Ravina, M.C. Rosa, I. Galve-Roperh , C. Sánchez , G. Velasco and L. González-Feria.

Due to its ability to inhibit tumor growth in animals, THC and other cannabinoids have been suggested as antitumor drugs. This is the first clinical study to test the application of THC in human patients with recurrent glioblastoma multiforme. The results demonstrate the safety profile of THC and its action on tumor cells, which establishes the basis for future trials. View study

09/27/2018

Author(s): Aine B Henley, Alistair V Nunn, Gary S Frost, Jimmy D Bell.

CBD possesses properties that, through “priming”, make it a potentially important adjunct to standard chemotherapy. Pre-treating tumour cells with a “priming agent” prior to the chemotherapeutic agent can enhance the efficacy of standard therapies. View study

09/27/2018

Author(s): Jahan P. Marcu1 , Rigel T. Christian1 , Darryl Lau1 , Anne J. Zielinski1 , Maxx P. Horowitz1 , Jasmine Lee1 , Arash Pakdel1 , Juanita Allison1 , Chandani Limbad1 , Dan H. Moore1,2, Garret L. Yount1 , Pierre-Yves Desprez1 , and Sean D. McAllister1.

Adding cannabidiol to Δ9-THC may improve the effectiveness of Δ9-THC in the treatment of glioblastoma in patients with cancer. When treating the cells with both compounds it was observed that these acted synergistically to inhibit cell proliferation. View study

09/27/2018

Author(s): Ana Juknat, Ewa Kozela, Nathali Kaushansky, Raphael Mechoulam and Zvi Vogel.

The results of this study indicate that cannabinoid receptors have a protective role against apoptosis induced by endocannabinoid anandamide (AEA) through vanilloid receptors. View study

09/27/2018

Author(s): Paola Massi, Marta Solinas, Valentina Cinquina and Daniela Parolaro.

There is emerging evidence to suggest that cannabidiol (CBD) is a potent inhibitor of cancer growth and spread. Its effectiveness is linked to its ability to target multiple cellular pathways that control tumorigenesis through the modulation of different intracellular signals depending on the type of cancer considered. View study

09/27/2018

Author(s): Maurizio Bifulco, 2 Chiara Laezza, 1 Simona Pisanti & 1 Patrizia Gazzerro.

Cannabinoids have the ability to selectively affect tumor cells more than their untransformed counterparts that may even be protected from cell death. These findings suggest that the cannabinoid system represents a promising target for cancer treatment. View study

09/27/2018

Author(s): Guillermo Velasco, Ismael Galve-Roperh, Cristina Sa´nchez, Cristina Bla´zquez, Amador Haro, Manuel Guzma´nT.

This study suggests that endocannabinoids constitute a new family of lipid signaling cues responsible for the regulation of the development and survival of neuronal cells, and provide a conceptual and mechanical basis for the effects of cannabinoids derived from marijuana. These findings provide a new conceptual view of how cannabinoids act and pose interesting physiological and therapeutic questions. However, more research is needed to determine the real impact of cannabinoids on brain development and the possible participation of ceramide in these events. View study

09/27/2018

Author(s): Bandana Chakravarti, Janani Ravi and Ramesh K. Ganju.

Cannabinoids derived from different sources can regulate different signaling pathways, modulate different types of tumor cells and the physiological system of the host. View study

09/27/2018

Author(s): Arkaitz Carracedo, Meritxell Gironella, Mar Lorente, Stephane Garcia, Manuel Guzmán, Guillermo Velasco, and Juan L. Iovanna.

Cannabinoids have the property of causing the death of pancreatic tumor cells through a CB2 receptor. This and other findings in this study can help establish the basis for a new type of therapy for pancreatic cancer. View study

09/27/2018

Author(s): Manuel Guzmán.

Cannabinoids have properties with positive effects in the treatment against cancer. They inhibit nausea and vomiting caused by chemotherapy while stimulating appetite and reducing pain. It has also been shown to inhibit tumor growth in laboratory animals. These findings can lay the foundation for future trials aimed at evaluating the possible anti-volume activity of cannabinoids in humans. View study

09/27/2018

Author(s): Teresa Gómez del Pulgar, María L. de Ceballos, Manuel Guzmán, and Guillermo Velasco.

Cannabinoids protect astrocytes from cell death induced by ceramide, which is an important evidence of the “astrofringent” role of cannabinoids. View study

09/27/2018

Author(s): M Solinas, P Massi, AR Cantelmo, MG Cattaneo, R Cammarota, D Bartolini, V Cinquina, M Valenti, LM Vicentini, DM Noonan, A Albini and D Parolaro.

Cannabidiol can inhibit angiogenesis (a physiological process that consists in the formation of new blood vessels from pre-existing vessels) through different mechanisms. Based on the results of this study, it is demonstrated that cannabidiol has the potential to be used as an effective agent in cancer therapy. View study