Safety Archives - Purablis-Medicinal Tinctures with CBD, THCA and THC

Safety Marijuana Studies and

Safety Cannabis Research


Author(s): Luciano Rezende Vilela, Lindisley Ferreira Gomides, Bruna Araújo David, Maísa Mota Antunes, Ariane Barros Diniz, Fabrício de Araújo Moreira, and Gustavo Batista Menezes.

The cannabinoid system may have an important role in the treatment of cocaine abuse, since its activation produces protective actions in the brain and liver, minimizing inflammatory lesions. View study


Author(s): Elspeth E.Pickering, Stephen J. Semple, Muhummad S. Nazir, Kevin Murphy, Thomas M. Snow, Andrew R. Cummin, Shakeeb H. Moosavi, Abraham Guz, and Anita Holdcroft.

To test the hypothesis that unpleasant respiratory problems will improve in humans with cannabinoids without respiratory depression, a double-blind, randomized, placebo-controlled study with two days of testing in five subjects with normal chronic obstructive pulmonary disease ( COPD) and four other subjects. After administering the drug, subjects with COPD experienced dyspnea (shortness of breath) less frequently than placebo. However, a more specific stimulus for “air hunger” may be necessary in order to directly demonstrate an


Author(s): Giovanni Marsicano, Sharon Goodenough, Krisztina Monory, Heike Hermann, Matthias Eder, Astrid Cannich, Shahnaz C. Azad, Maria Grazia Cascio, Silvia Ortega Gutie´rrez, Mario van der Stelt, Maria Luz Lo´pez-Rodrı´guez, Emilio Casanova, Gu¨nther Schu¨tz, Walter Zieglga¨nsberger, Vincenzo Di Marzo, Christian Behl, Beat Lutz.

The endogenous cannabinoid system provides on-demand protection against acute excitotoxicity in neurons of the central nervous system. View study


Author(s): Carol Hamelink, Aidan Hampson, David A. Wink, Lee E. Eiden, and Robert L. Eskay.

Cannabidiol (CBD) was evaluated as a neuroprotector in a borage model of ethanol. When administered at the same time as excessive exposure to ethanol, CBD protects against hippocampal and entorhinal cortical neurodegeneration in a dose-dependent manner. This study provides the first demonstration of CBD as a neuroprotective in vivo and shows the efficacy of lipophilic antioxidants in the prevention of brain lesions induced by excess ethanol. View study