Cancer Medical Cannabis Studies

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Cannabidiol Inhibits Growth and Induces Programmed Cell Death in Kaposi Sarcoma�Associated Herpesvirus Infected Endothelium (2012)

Cannabidiol has properties that inhibit the expression of the herpesvirus receptor associated with Kaposi’s sarcoma, which leads to taking cannabidiol under clinical consideration for the treatment of Kaposi’s sarcoma. View study
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1 (2012)

Cannabinoids have the property of inhibiting the invasion of cancer cells by inducing the intercellular adhesion molecule-1 (ICAM-1), which in turn confers the induction of the tissue inhibitor of matrix metallo-proteinases-1 (TIMP-1). View study
Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma (2009)

According to the results of this study, cannabinoid receptors have been shown to have antitumor properties in vitro and, for the first time, in vivo. This could represent a possible new treatment strategy that could improve the results in translocation-positive rhabdomyosarcoma. View study
Cannabinoid Receptor Agonist as an Alternative Drug in 5-Fluorouracil-resistant Gastric Cancer Cells (2013)

The cannabinoid agonist WIN 55,212-2 is able to induce cytotoxicity in gastric cancer cells resistant to 5-FU. These results indicate that cannabinoids have potential to be used as therapy against gastric cancer resistant to 5-FU. View study
Cannabinoid receptor ligands as potential anticancer agents � high hopes for new therapies (2009)

It is possible that cannabinoids have anticancer effects in the appropriate context, although their effects may not be significant enough for chemotherapy. Future studies will be able to demonstrate whether cannabinoids or cannabimimetic agents have the ability to reduce tumor growth in vivo synergistically with chemotherapeutic agents. View study
Cannabinoid Receptor-Mediated Apoptosis Induced by R()-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (2006)

The CB1 and CB2 receptors may have a great therapeutic potential for the treatment of mantle cell lymphoma. View study
Cannabinoid receptors as novel targets for the treatment of melanoma (2006)

The activation of cannabinoid receptors CB1 and CB2 succeeded in reducing the growth, proliferation, angiogenesis and metastasis, and the increase of apoptosis, of melanomas in mice. This discovery may contribute to the design of new chemotherapeutic strategies for the treatment of melanoma. View study
Cannabinoid Receptors, CB1 and CB2, as Novel Targets for Inhibition of Non-Small Cell Lung Cancer Growth and Metastasis (2011)

The cannabinoid receptors CB1 and CB2 have the potential to become therapeutic targets against non-small cell lung cancer. In this study it was demonstrated that the treatment of cell lines of this type of cancer with CB1 / CB2 and CB2-specific agonists Win55, 212-2 and JWH-015 significantly reduced both the growth factor-directed in vitro chemotaxis and chemoinvasion in these cells. View study
Cannabinoid-associated cell death mechanisms in tumor models (Review) (2012)

Cannabinoids have been shown to possess certain anti-cancer qualities. A more in-depth exploration of the molecular mechanisms induced by cannabinoids on cancer cells could contribute to the development of safe and effective treatments in cancer therapy. View study
Cannabinoids and Cancer (2005)

Cannabinoids have some anticancer properties, in addition to stimulating appetite, attenuate pain, inhibit nausea and vomiting. It is possible that cannabinoids can represent a new type of drugs with great utility in the fight against cancer, slowing its growth, inhibiting angiogenesis and metastatic spread of cancer cells. View study
Cannabinoids and cancer: pros and cons of an antitumour strategy (2006)

Cannabinoids have the ability to selectively affect tumor cells more than their untransformed counterparts that may even be protected from cell death. These findings suggest that the cannabinoid system represents a promising target for cancer treatment. View study
Cannabinoids and ceramide: Two lipids acting hand-by-hand (2005)

This study suggests that endocannabinoids constitute a new family of lipid signaling cues responsible for the regulation of the development and survival of neuronal cells, and provide a conceptual and mechanical basis for the effects of cannabinoids derived from marijuana. These findings provide a new conceptual view of how cannabinoids act and pose interesting physiological and therapeutic questions. However, more research is needed to determine the real impact of cannabinoids on brain development and the possible participation of ceramide in these events. View study