Pain Medical Cannabis Studies

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Benefits and adverse effects of cannabis use among adults with persistent pain (2018)

Increasingly, states are legalizing cannabis for recreational use. Improved accessibility can allow adults with pain to use cannabis more liberally. The purpose of this study was to examine the perceived effects of cannabis in adults who have been prescribed opioids for persistent pain. View study
Benefits and Harms of Cannabis in Chronic Pain or Post-traumatic Stress Disorder: A Systematic Review [Internet] (2017)

Recent studies indicate that between 45% and 80% of people who seek cannabis for medical purposes do so to control pain, which suggests its therapeutic potential in patients with chronic pain. View study
Canabimimetic plants: are they new cannabinoidergic modulators. (2019)

The objective of this review was to provide critical and complete assessment of the botanical, chemical and therapeutic aspects of cannabimimetic plants to evaluate their spread in the world and medicinal potentiality. View study
Cannabinoid Buccal Spray for Chronic Non-Cancer or Neuropathic Pain: A Review of Clinical Effectiveness, Safety, and Guidelines [Internet] (2016)

The objective of this research is to review the available published literature related to the oral spray THC: CBD for the treatment of chronic neuropathic or neuropathic pain in adults. Studies have been conducted on the therapeutic use of various synthetic cannabinoid products for the symptomatic relief of chronic pain. View study
Cannabinoid Delivery Systems for Pain and Inflammation Treatment. (2018)

This review aimed to explore the most recent developments, from preclinical to advanced clinical trials, in the field of cannabinoid administration, and focuses particularly on the treatment of pain and inflammation. Future probable directions are also considered and reported. View study
Cannabinoids for fibromyalgia (2016)

Fibromyalgia is a clinically well defined chronic condition of unknown etiology characterized by chronic widespread pain that often coexists with sleep and fatigue problems that affect approximately 2% of the general population. The present review focused on evaluating the efficacy, tolerability and safety of cannabinoids for the symptoms of fibromyalgia in adults. It could be concluded that no convincing, impartial and high quality evidence was found to suggest that nabilone is valuable in the treatment of people with fibromyalgia. The tolerability of nabilone was low in people with fibromyalgia. View study
Cannabinoids for treatment of chronic non-cancer pain: a systematic review of randomized trials (2011)

Cannabinoids are safe and more effective for the treatment of neuropathic pain with preliminary evidence of efficacy in fibromyalgia and rheumatoid arthritis without serious adverse effects. View study
Cannabis products for adults with chronic neuropathic pain (2018)

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Cannabis products for people with fibromyalgia ()

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Cannabis-based medicines for chronic neuropathic pain in adults. (2018)

Cannabis has been used for millennia to reduce pain. Herbal cannabis is currently strongly promoted by some patients and their advocates to treat any type of chronic pain.The present review aimed to evaluate the efficacy, tolerability and safety of cannabis-based medicines (herbal, derived of plants, synthetic) compared to conventional medications or placebo for conditions with chronic neuropathic pain in adults. View study
Gabapentin for Adults with Neuropathic Pain: A Review of the Clinical Evidence and Guidelines [Internet] (2014)

The purpose of this review is to investigate the clinical evidence on the efficacy and safety of the use of gabapentin in adults with neuropathic pain. In this investigation, it could be concluded that there is little evidence on the abuse and misuse of pregabalin, but existing data suggest that some populations with a history of substance abuse may be at increased risk of pregabalin abuse. View study
Gender differences in associations between pain-related anxiety and alcohol use among adults with chronic pain. (2019)

It has been shown that pain motivates the need and consumption of alcohol, and drinking to cope with pain predicts escalations in alcohol consumption over time. This research seeks to perform the first test of cross-sectional associations between anxiety related to pain, sex and alcohol consumption. View study
Interventions for Atypical Facial Pain: A Review of Clinical Effectiveness and Guidelines [Internet] (2011)

Atypical facial pain (AFP), also known as persistent idiopathic facial pain (PIFP), is a chronic disorder involving lancinating pain located in the craniofacial region that is not characteristic of common cranial neuralgia and that does not It has apparent cause. The purpose of this report was to review available published literature related to pharmacological and non-pharmacological interventions for the treatment of atypical facial pain (AFP) in adults. View study
Long-term Nabilone Use: A Review of the Clinical Effectiveness and Safety [Internet] (2015)

In this report we summarize the evidence of clinical efficacy and safety in the damages associated with the long-term use of nabilone in adults with post-traumatic stress disorder (PTSD) and other chronic conditions. The results showed that nabilone appeared to be safe and effective for the treatment of nightmares related to post-traumatic stress disorder and for pain and spasticity for up to nine weeks of treatment. View study
Medical Cannabis in Residential Transition or Addiction Programs: A Review of Clinical and Cost-Effectiveness and Guidelines [Internet] (2017)

Medical cannabis has many preparations and methods of administration that are used medically to treat a variety of chronic and acute conditions. The objective of this report is to review the clinical effectiveness, cost-effectiveness and evidence-based guidelines regarding the use of medical cannabis to treat adults with addiction in residential transition / addiction programs. View study
Medical cannabis use among patients with chronic pain in an interdisciplinary pain rehabilitation program: Characterization and treatment outcomes (2017)

Cannabis is increasingly used in the treatment of chronic pain. The present investigation examines the clinical and treatment characteristics of patients admitted to an interdisciplinary 3-week chronic pain rehabilitation program. The results obtained provide preliminary evidence that patients with chronic pain who consume cannabis can benefit from an interdisciplinary chronic pain program. View study
Medical Cannabis Use Is Associated With Decreased Opiate Medication Use in a Retrospective Cross-Sectional Survey of Patients With Chronic Pain (2016)

Opioids are commonly used to treat patients with chronic pain (PC), although there is little evidence that they are effective for long-term (PC) treatment. The present investigation focused on examining whether medicinal cannabis (PC) consumption changed individual patterns of opioid use. View study
Medical cannabis: considerations for the anesthesiologist and pain physician. (2016)

This article aims to present new regulations along with one with a guide for the safe use of medicinal cannabis and recent clinical trials on cannabis and pain. It could be concluded that although cannabinoids work to decrease pain, there is still a need to confirm these beneficial effects clinically and to exploit them with acceptable benefit-to-risk ratios. View study
Medical Marijuana for Post-Traumatic Stress Disorder: A Review of Clinical Effectiveness and Guidelines [Internet] (2017)

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can occur after experiencing a traumatic, shocking or frightening event, such as injury, violence or death. The objective of this summary is to present clinical efficacy evidence for medical marijuana and synthetic cannabinoids in adult populations with posttraumatic stress disorder and to identify any evidence-based guidelines for this population. View study
Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain (2007)

Cannabinoids are associated with a clinically remarkable and statistically significant depreciation of pain scores. The study that compared changes with respect to onset and effectiveness with respect to placebo was not clearly established. Also, the clinical significance of the observed effects was not clear. The included studies had small sample sizes and were of short-term treatment, and this should also be taken into account when interpreting the results. Given the limitations of the evidence presented, the reliability of the authors’ conclusions is uncertain. View study
Nabilone for Non-chemotherapy Associated Nausea and Weight Loss due to Medical Conditions: A Review of the Clinical Effectiveness and Guidelines [Internet] (2014)

This report will review the evidence of the medical effectiveness and safety of nabilone when used for the treatment of nausea and vomiting unrelated to chemotherapy and to control weight loss attributed to medical conditions. Nabilone is a synthetic cannabinoid analogue of delta-9-tetrahydrocannabinol (THC). Nabilone has a therapeutic effect by acting as an agonist in the CB1 cannabinoid receptor, a receptor that plays a role in the regulation of nausea and vomiting, appetite, movement and pain. View study
Neuromodulators for pain management in rheumatoid arthritis (2012)

This research focused on the study of the efficacy and safety of neuromodulators in the treatment of pain in patients with rheumatoid arthritis (RA). According to the results obtained in this research, it could be concluded that there is weak evidence that oral nefopam, topical capsaicin and oromucosal cannabis are all superior to placebo in reducing pain in patients with RA. Confidence in our estimates is not strong given the difficulties with blinding, the small number of participants evaluated and the lack of adverse event data. In some patients, however, even a small degree of pain relief can be considered valuable. It is advisable to carry out future research and obtain more information about it. View study
Oxycodone for neuropathic pain and fibromyalgia in adults. (2014)

This review is part of a series of medications used to treat neuropathic pain and fibromyalgia. It is estimated that these conditions affect 3 to 10% of adults and are difficult to treat. Although they probably have different etiologies, neuropathic pain and fibromyalgia can respond to the same therapies. The purpose of this research was to evaluate the analgesic efficacy and adverse events of oxycodone for chronic neuropathic pain and fibromyalgia. View study
Primary Care Behavioral Interventions to Prevent or Reduce Illicit Drug and Nonmedical Pharmaceutical Use in Children and Adolescents: A Systematic Evidence Review for the U.S. Preventive Services Task Force [Internet] (2014)

The present research was based on the systematic study of the evidence on the benefits and harms of important interventions for primary care designed to reduce the use of illicit drugs or the non-medical use of prescription drugs in children and adolescents. View study

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Pain Medical Cannabis Studies