Colon-Cancer Medical Cannabis Studies

A

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B

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C

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E

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F

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I

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P

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T

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• View All (505)
  • Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha-mediated ceramide de novo synthesis in colon cancer cells (2008)

    Recently, cannabinoids have been proposed as possible antitumor agents. This study investigates the expression of the two cannabinoid receptors, CB1 and CB2, in colorectal cancer, revealing for the first time that TNF-a acts as a link between the activation of the cannabinoid receptor and the production of ceramide. View study

  • Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer (2012)

    CBD exerts antioxidant, intestinal, anti-inflammatory actions and potentially beneficial mechanisms for colon carcinogenesis. This study investigates its chemopreventive effects and the reduction of cell proliferation through multiple mechanisms. View study

  • Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines (2008)

    Cannabinoids have the ability to activate cannabinoid receptors CB1 and CB2. It is possible to control the proliferation of colon cancer by an additional mechanism of regulation by increasing the expression of CB1 by 17b-estradiol. View study

  • Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors (2001)

    In this investigation a study of the growth inhibition and the induction of apoptosis in colorectal tumor cells by inhibitors of cyclooxygenase is made. The data show that both COX-dependent cyclooxygenase-dependent mechanisms and COX-independent mechanisms are involved in the growth induced by non-steroidal anti-inflammatory drugs (NSAIDs) in colorectal tumor cells. View study

  • Induction of Apoptosis by Cannabinoids in Prostate and Colon Cancer Cells Is Phosphatase Dependent (2011)

    Cannabinoid receptor agonists induce phosphatases and phosphatase-dependent apoptosis in cancer cell lines; however, the role of the CB receptor in mediating this response depends on the ligand. View study

  • Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol (2013)

    This research showed that using a cannabis extract with high content of cannabidiol (CBD) called (CBD) (BDS) botanical pharmacological substance (CBD). It can attenuate the carcinogenesis of the colon and prevent the reproduction of colorectal cancer cells by activating the CB1 and CB2 receptor. View study

  • Possible endocannabinoid control of colorectal cancer growth (2003)

    Endocannabinoids are produced in excess in cancerous tissue and particularly in the precancerous colon and help to inhibit the growth of colorectal cancer cells in the culture, in which the degree of action and levels appear to depend on the degree of differentiation and malignancy / invasiveness of these cells. View study

  • The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells (2010)

    This research was based on the study of the potential efficacy of endogenous cannabinoid anandamide to induce cell death in colon cancer cells resistant to apoptosis. View study