Medical Cannabis Studies

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Cannabinoids Protect Astrocytes from Ceramide-induced Apoptosis through the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway (2002)

Cannabinoids protect astrocytes from cell death induced by ceramide, which is an important evidence of the astrofringent role of cannabinoids. View study
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition (2010)

Preclinical evidence indicating the possible efficacy of the use of cannabidoids in the treatment of ErbB2-positive breast cancer, characterized by highly aggressive phenotypes and a reduced response to standard therapies. View study
Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells (2005)

D9-tetrahydrocannabinol (D9-THC) can decrease cell proliferation and increases cell death of gliobastoma multiforme (GBM) cells in humans more rapidly and effectively than the synthetic cannabinoid agonist WIN 55,212-2. View study
Cannabinoids stimulate the TRP-channel dependent release of both serotonin and dopamine to modulate behavior in C. elegans. (2019)

The purpose of this study was to highlight the advantages of identifying and evaluating CB1 / CB2 dependent and independent cannabinoid signaling pathways in a genetically treatable mammalian predictive model, in which cannabinoid signaling at the molecular / neuronal level can directly correlate with changes in behavior View study
Cannabinoids, Endocannabinoids and Cancer (2012)

Cannabinoids are involved in the reduction of tumor growth and metastasis, and the induction of apoptosis. This study demonstrates that combination therapy that uses both traditional chemotherapeutics and molecules targeted to the endocannabinoid system can be an excellent next-generation treatment for cancer. View study
Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation (2008)

Cannabinoids promote the induction of the anti-inflammatory process according to this revision. Which is intended to be an update on the issue of the participation of cannabinoids in the inflammation process View study
Cannabinoids, Immune System and Cytokine Network (2006)

There is sufficient evidence to suggest that the cannabinoid system affects significantly all the components of the immune response machinery and impacts the functioning also of the cytokine network. View study
Cannabinoids, inflammation, and fibrosis (2016)

This review focuses on the clear evidence of the positive anti-inflammatory effects of phytocannabinoids D9 -tetrahydrocannabinol (THC), cannabidiol, cannabichromen and cannabinol.Therefore, several cannabinoids can be considered key elements for development as anti-inflammatory and antifibrotic agents View study
Cannabinoids: A new hope for breast cancer therapy (2012)

Cannabinoid-based drugs may be useful for the treatment of most subtypes of mammary tumors. View study
Cannabinoids: potential antitumoral agents (2006)

Cannabinoids have properties with positive effects in the treatment against cancer. They inhibit nausea and vomiting caused by chemotherapy while stimulating appetite and reducing pain. It has also been shown to inhibit tumor growth in laboratory animals. These findings can lay the foundation for future trials aimed at evaluating the possible anti-volume activity of cannabinoids in humans. View study
Cannabinomimetic Control of Mast Cell Mediator Release: New Perspective in Chronic Inflammation (2008)

The purpose of this research was to clarify the emerging role played by cannabinomimetic compounds in the control of mast cell activation. The results gave evidence that cannabinomimetic compounds, including palmitoylethanolamide and its congeners, could represent potential candidates for the treatment of several chronic diseases. View study
Cannabis and Amyotrophic Lateral Sclerosis: Hypothetical and Practical Applications, and a Call for Clinical Trials (2010)

It has been demonstrated Cannabis could significantly delay the progression of amyotrophic lateral sclerosis, increasing life expectancy and alleviating the burden of the disease…. View study