Medical Cannabis Studies

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Involvement of PPARc in the antitumoral action of cannabinoids on hepatocellular carcinoma (2013)

The cannabinoids D9-tetrahydrocannabinol and JWH-015 have the ability to exert an antitumor effect against human hepatocellular carcinoma cell lines HepG2 and HUH-7 in vitro and in vivo through PPARg (peroxisome proliferator-activated gamma receptor). View study
Involvement of the endocannabinoid system in drug addiction (2006)

Due to their properties, CB1 cannabinoid antagonists could contribute to the treatment of drug addiction, allowing the development of pharmacological compounds that can be used safely. View study
Is cannabis treatment for anxiety, mood, and related disorders ready for prime time? (2017)

Anxiety and related disorders are the most common mental conditions that affect people in North America. Cannabis is commonly seen as a natural alternative to a variety of medical and mental health conditions. The purpose of this article is to provide a comprehensive review of the current literature on the treatment of cannabis and to identify the potential of cannabis as a therapeutic intervention for anxiety, mood and related disorders. View study
Is the cardiovascular system a therapeutic target for cannabidiol? (2012)

Cannabidiol, in addition to its beneficial effects in many disorders, can also be important for the treatment of cardiovascular diseases, since it acts directly on the isolated arteries and causes vasorelaxation. View study
Joint Effects: A Pilot Investigation of the Impact of Bipolar Disorder and Marijuana Use on Cognitive Function and Mood (2016)

The objective of this research was to determine the impact of marijuana on mood in bipolar patients and to verify if marijuana confers an additional negative impact on cognitive function. View study
Keep off the grass Cannabis? Cognition and addiction (2016)

The use of cannabis in a short futon in many countries as well as tobacco and alcohol will be of legal use. This study reviews the current state of knowledge about vulnerability factors, variations in the types of cannabis and the relationship between these and cognition and addiction. View study
Long-term Nabilone Use: A Review of the Clinical Effectiveness and Safety [Internet] (2015)

In this report we summarize the evidence of clinical efficacy and safety in the damages associated with the long-term use of nabilone in adults with post-traumatic stress disorder (PTSD) and other chronic conditions. The results showed that nabilone appeared to be safe and effective for the treatment of nightmares related to post-traumatic stress disorder and for pain and spasticity for up to nine weeks of treatment. View study
Loss of Cannabinoid Receptor 1 Accelerates Intestinal Tumor Growth (2008)

Aberrant methylation of the cannabinoid receptor 1 (CB1) represents a clear mechanism for combating colorectal cancer (CRC). Through different approaches, in vivo evidence was found that shows that endocannabinoid signaling through CB1 plays a key role in the regulation of intestinal tumor growth. These results may provide a rationale for the development of CB1 agonists that do not cross the blood-brain barrier and that can be used to prevent and treat cancer in combination with a demethylating agent. View study
Marijuana Rated Most Effective for Treating Fibromyalgia (2014)

It has been found in research and tests that medical marijuana is much more effective for the treatment of fibromyalgia than the three prescription drugs approved by the National Foundation of Pain and the National Pain Report. The FDA. View study
Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (2006)

These studies indicate that marijuana is not carcinogenic or has a percentage well below the practically detectable limits to be, in opposition to various lines of evidence suggesting otherwise. View study
Marijuana Use in Epilepsy: The Myth and the Reality (2015)

In recent years the interest for the use of cannabinoids for the treatment of epilepsy has grown. This review answers the most significant questions that doctors have about the use of cannabis in the treatment of epilepsy. View study
Marijuana Use Patterns Among Patients with Inflammatory Bowel Disease (2013)

The objective of this research was to assess the prevalence, sociodemographic characteristics and perceived benefits of marijuana use in patients with inflammatory bowel disease (IBD). The results of this study indicate that a large number of patients consume marijuana. Most patients find it very useful for the control of symptoms, including patients with ulcerative colitis. More studies are needed on marijuana as an IBD therapy View study