Medical Cannabis Studies

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Marijuana- interaction with the estrogen receptor (1982)

This research was based on the study of marijuana and its interaction with the estrogen receptor. The results showed that although estrogen receptor binding activity was observed in the crude marijuana extract, the marijuana smoke condensate and several known components of cannabis, the direct estrogenic activity of the cannabis extract could not be demonstrated in vivo. View study
Marijuana, Tetrahydrocannabinol, and Pulmonary Antibacterial Defenses (1980)

This research was based on studying the biological effects of marijuana, tetrahydrocannabinol in the lung. The results gave clear evidence that marijuana smoke is toxic to the lungs and is toxic to the pulmonary antibacterial defense system in a manner dependent on the dose. View study
Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: Role of 5HT1A and CB2 receptors (2013)

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Medical Cannabis in Residential Transition or Addiction Programs: A Review of Clinical and Cost-Effectiveness and Guidelines [Internet] (2017)

Medical cannabis has many preparations and methods of administration that are used medically to treat a variety of chronic and acute conditions. The objective of this report is to review the clinical effectiveness, cost-effectiveness and evidence-based guidelines regarding the use of medical cannabis to treat adults with addiction in residential transition / addiction programs. View study
Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States, 1999-2010 (2014)

Based on the results of this study, it was determined that the medical laws on cannabis are associated with significantly lower death rates from opioid overdoses at the state level. Deeper studies are required to determine how medical cannabis laws can interact with policies aimed at preventing overdoses of opioid analgesics. View study
Medical cannabis use among patients with chronic pain in an interdisciplinary pain rehabilitation program: Characterization and treatment outcomes (2017)

Cannabis is increasingly used in the treatment of chronic pain. The present investigation examines the clinical and treatment characteristics of patients admitted to an interdisciplinary 3-week chronic pain rehabilitation program. The results obtained provide preliminary evidence that patients with chronic pain who consume cannabis can benefit from an interdisciplinary chronic pain program. View study
Medical Cannabis Use Is Associated With Decreased Opiate Medication Use in a Retrospective Cross-Sectional Survey of Patients With Chronic Pain (2016)

Opioids are commonly used to treat patients with chronic pain (PC), although there is little evidence that they are effective for long-term (PC) treatment. The present investigation focused on examining whether medicinal cannabis (PC) consumption changed individual patterns of opioid use. View study
Medical cannabis: considerations for the anesthesiologist and pain physician. (2016)

This article aims to present new regulations along with one with a guide for the safe use of medicinal cannabis and recent clinical trials on cannabis and pain. It could be concluded that although cannabinoids work to decrease pain, there is still a need to confirm these beneficial effects clinically and to exploit them with acceptable benefit-to-risk ratios. View study
Medical Cannabis. (2018)

Patients increasingly ask physicians to share information about them or to certify them for medical cannabis. The objective of this review was to provide a general description of the legal status, pharmacology, benefits, risks and responsibility of abuse. of medicinal cannabis together with a general framework to advise patients. View study
Medical marijuana for cancer (2015)

Pharmaceutical cannabis and cannabinoid products can be useful for a large number of problems, including many that affect cancer patients. High-quality marijuana and cannabinoid pharmaceutical studies in the treatment of a range of medical conditions would better clarify the clinical effects of the various strains of marijuana and the bioactive compounds found therein. Differences in pharmacokinetics between oral ingestion and inhalation may point to differences in clinical effect for different indications. For example, given the limitations inherent in the use of oral medications to treat nausea and vomiting, the inhalation of marijuana or a cannabinoid may be better than oral ingestion to treat this condition. View study
Medical Marijuana for Post-Traumatic Stress Disorder: A Review of Clinical Effectiveness and Guidelines [Internet] (2017)

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can occur after experiencing a traumatic, shocking or frightening event, such as injury, violence or death. The objective of this summary is to present clinical efficacy evidence for medical marijuana and synthetic cannabinoids in adult populations with posttraumatic stress disorder and to identify any evidence-based guidelines for this population. View study
Medical Marijuana Use in a Community Cancer Center. (2018)

The objective of the present investigation was to compare the incidence of marijuana use among patients with early versus advanced cancer. It was concluded that approximately one out of every five cancer patients receiving chemotherapy was using marijuana, and the frequency was the same in the early and advanced stage cancer groups. View study