Medical Cannabis Studies

• View All (505)

Medical use of cannabis in patients with HIV/AIDS. (2013)

Cannabis can help in the treatment of AIDS-related anorexia, and is said to improve appetite, which results in weight gain and better mood, thus improving the quality of life. View study
Medications for the treatment of cannabis dependence (2014)

Effectiveness and safety of pharmacotherapies in the treatment of cannabis use disorders and the reduction of withdrawal symptoms. View study
Medicinal cannabis in oncology (2007)

This review focused on analyzing the background of the introduction of legal medical cannabis in the Netherlands, the last years of Dutch clinical experience in the practice of oncology, the possible reasons that underlie the current result and future prospects. View study
Melanoma: Assessment and Management (2015)

Cutaneous melanoma is increasing in incidence in many of the developed countries, since this form of cancer occurs predominantly in people with pale skin who are exposed to intense sunlight. Male sex and age are two factors of poor prognosis for melanoma. This study focused on the evaluation and management of Melanoma. View study
Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain (2007)

Cannabinoids are associated with a clinically remarkable and statistically significant depreciation of pain scores. The study that compared changes with respect to onset and effectiveness with respect to placebo was not clearly established. Also, the clinical significance of the observed effects was not clear. The included studies had small sample sizes and were of short-term treatment, and this should also be taken into account when interpreting the results. Given the limitations of the evidence presented, the reliability of the authors’ conclusions is uncertain. View study
Method for predicting autism spectrum disorders by cannabinoid and cannabinoid receptor expression (2012)

View study
Methods of the Pharmacological Imaging of the Cannabinoid System (PhICS) study: towards understanding the role of the brain endocannabinoid system in human cognition (2011)

This article narrates the objectives and methods of the pharmacological image study of the PhICS cannabinoid system and shows the preliminary results of the administration procedure on subjective and neurophysiological parameters. The preliminary results presented in this document indicate solid behavioral and subjective effects of the acute effects of the Cannabinoid agonist 9-tetrahydrocannabinol (THC). View study
Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells (2013)

Cannabidiol (CBD) can elicit robust responses that are related to oxidative stress and inflammation. In addition, CBD and, to a lesser extent, D9-tetrahydrocannabinol (THC), have protective activities and decrease the immunological activity of the organism in response to medical treatment. View study
Mitochondria: a possible nexus for the regulation of energy homeostasis by the endocannabinoid system (07/01/05)

This research focuses on studying the different ways in which ECS can impact mitochondrial abundance and / or oxidative capacity, and link these findings with the obesity-induced perturbations in metabolic function View study
Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent (2016)

Treatment with JWH-015 was able to significantly decrease the primary tumor burden and the metastasis of luciferase-labeled murine breast carcinoma 4T1 cells in immunocompetent mice in vivo. It also reduced the viability of murine 4T1 and MCF7 breast carcinoma cells in vitro by inducing apoptosis. Based on these results, JWH-015 and other selective CB2 agonists (cannabinoid receptor 2) demand attention as adjuvant therapies, particularly in patients undergoing bone metastases where the CB2-selective compounds can not only improve the outcome of the disease but also increase the quality of life of the patient. View study
Motor effects of delta 9 THC in cerebellar Lurcher mutant mice (2007)

In the study, the motor effects of delta 9 tetrahydrocannabinol (delta 9 THC) were evaluated in Lurcher brain mutant mice. It was observed that cannabinoid substance (CB) reduced deficits in motor coordination, balance and muscle tone and facilitated motor learning in Lurche mice. View study
Nabilone for Non-chemotherapy Associated Nausea and Weight Loss due to Medical Conditions: A Review of the Clinical Effectiveness and Guidelines [Internet] (2014)

This report will review the evidence of the medical effectiveness and safety of nabilone when used for the treatment of nausea and vomiting unrelated to chemotherapy and to control weight loss attributed to medical conditions. Nabilone is a synthetic cannabinoid analogue of delta-9-tetrahydrocannabinol (THC). Nabilone has a therapeutic effect by acting as an agonist in the CB1 cannabinoid receptor, a receptor that plays a role in the regulation of nausea and vomiting, appetite, movement and pain. View study