Medical Cannabis Studies

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Tolerance to the memory disruptive effects of cannabinoids involves adaptation by hippocampal neurons (2003)

Tolerance to repeated exposure to cannabinoids is of major significance, given the number of cellular and synaptic processes shown to be coupled to cannabinoid receptors in the brain. This research was based on the study of tolerance to the detrimental effects of cannabinoid memory involving the adaptation of hippocampal neurons, using rats. View study
Toward Drugs Derived from Cannabis (2004)

Glaucoma is one of the leading causes of blindness in the world. The objective of this review is to provide an overview of the latest research achievements in the potential use of cannabinoids for glaucoma. View study
Treatment with CB2 Agonist JWH-133 Reduces Histological Features Associated with Erectile Dysfunction in Hypercholesterolemic Mice (2013)

Hypercholesterolemia is one of the most important risk factors for erectile dysfunction, mostly due to the impairment of oxidative stress and endothelial function in the penis. This research focused on the investigation of the effects of CB2 activation on oxidative stress and fibrosis in the corpus cavernosum of mice. View study
Trends in Publications on Medical Cannabis from the Year 2000. (2018)

The objective of the present research was to compare trends in scientific publications for articles on medicinal cannabis, articles on cannabis in general and all articles between 2000 and 2017. View study
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome (2017)

In this study, cannabidiol was used to treat seizures in patients with Dravet syndrome, and resulted in a greater reduction in seizure frequency. View study
Uncoupling of the endocannabinoid signaling complex in a mouse model of fragile X syndrome (2012)

The pharmacological potentiation of 2-arachidonoyl-sn-glycerol signaling normalizes the synaptic defect of depression and corrects behavioral abnormalities in mice with fragile X syndrome. The endocannabinoid signalosome is a molecular substrate for fragile X syndrome, which might be targeted by therapy. View study
Understanding Cannabinoids and Epilepsy (-)

Dr. James Bradstreet, an experienced and respected physician in the treatment of autism, epilepsy and associated disorders, indicates that cannabinoids can treat epilepsy. CBD and THC are effective in cases of epilepsy resistant to conventional treatments. View study
Use of dronabinol (delta-9-THC) in autism: A prospective single-case-study with an early infantile autistic child (2010)

In assessing the effectiveness of dronabinol as a complementary therapy in a child with autistic disorder, it was found that dronabinol can reduce the symptoms of autism. View study
Vaporization of Marijuana Among Recreational Users: A Qualitative Study. (2019)

The objective of the present qualitative study was to examine the cognitions related to vaping among recreational users of marijuana. It was concluded that Quantitative research is needed to examine the extent to which cognitions about marijuana vaporization contribute to current use patterns and problematic behaviors. View study
Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces (2011)

CNR1 modulates striatal function through which social reward signals are perceived, such as happy faces. These results suggest that CNR1 is a key element in the perception process of certain basic emotions. View study
Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se (2014)

Cannabidiol is a non-psychoactive cannabinoid, well tolerated and anticonvulsant. Here, we investigate the effects of CBD and the structurally similar cannabinoid cannabigerol (CBG), where CBG had no effect on seizures induced in animal models. View study
What every pediatric gynecologist should know about marijuana use in adolescents. (2019)

The use of marijuana in adolescents is common and shows no signs of diminishing. This research aimed to review the current literature on the risks and potential benefits of marijuana use during adolescence with a specific focus on pediatric and adolescent gynecological conditions. View study