Cancer Medical Cannabis Studies

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Neuropathic Pain: The Pharmacological Management of Neuropathic Pain in Adults in Non-specialist Settings [Internet] (2013)

Neuropathic pain is defined as pain that is initiated or caused by an injury or primary dysfunction in the nervous system. The objective of this clinical guide is to improve the care of adults with neuropathic pain by means of evidence-based recommendations on the pharmacological management of neuropathic pain outside of specialized services for pain management. View study
Non-Hodgkin's Lymphoma: Diagnosis and Management (2016)

The main function of this guide is to provide a standard practice in the treatment of non-Hodgkin’s lymphoma. Due mainly to the rapid development of new therapies as a result of a better understanding of the biology of the disease. View study
Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms (2012)

These studies support the clinical tests of the capacity and anticancer potential of cannabidiol (CBD), specifically against prostate cancer…. View study
Nutrition in Cancer Care (PDQ�): Health Professional Version (2017)

This report offers cancer-related information for health professionals, providing them with a comprehensive, expertly-verified, evidence-based review of nutrition before, during, and after cancer treatment. View study
Patterns of Medical Cannabis Use among Cancer Patients from a Medical Cannabis Dispensary in New York State (2019)

Research on the patterns of use of medical cannabis among cancer patients is lacking. This research aimed to describe patterns of medicinal cannabis use in patients with cancer, and how the patterns differ from patients without cancer. View study
Potentiation of Cannabinoid-Induced Cytotoxicity in Mantle Cell Lymphoma through Modulation of Ceramide Metabolism (2009)

This study suggests that R (+) - methanandamide has the ability to cause cell death in mantle cell lymphoma. View study
Potentiation of the antitumor activity of adriamycin against osteosarcoma by cannabinoid WIN-55,212-2 (2015)

Based on the results obtained in this study, the cannabinoid WIN-55,212-2 is antiproliferative, antimetastatic and antiangiogenic against MG-63 cells in vitro, and in addition, the cannabinoid WIN-55,212-2 can result in a synergistic antitumor action in combination with adriamycin against osteosarcoma. However, further in-depth studies are required to investigate the precise and complete molecular mechanisms of these antitumor activities, and whether this coadministration of cannabinoids and adriamycin could be effectively applied in practice. View study
Preparation and characterisation of biodegradable microparticles filled with THC and their antitumor efficacy on cancer cell lines (2013)

Cannabinoids have great pharmacological potential despite the difficulties they may present at the time of handling. However, in this work it was possible to efficiently encapsulate D9-tetrahydrocannabinol in polycaprolactone microparticles, which can be administered subcutaneously through a conventional needle. It was demonstrated that a single administration of these microparticles showed an antiproliferative effect during the 9 days of the experiment. In the future, these systems could be used in combination with other anti-cancer drugs or conventional therapies to increase therapeutic efficacy. View study
prostate cancer cell (2010)

Through this study it was possible to obtain evidence that fatty acid amide hydrolase (FAAH) metabolizes ethanolamide eicosapentaenoyl (EPEA) and ethanolamide docosahexaenoyl (DHEA) and that the antiproliferative potencies of these ethanolamides in LNCaP cells can be enhanced by inhibiting this enzyme. The findings suggest that the expression of cannabinoid receptors and (FAAH) in some tumor cells could influence the effectiveness of (DHA) and (EPA) or their ethanolamide derivatives as anticancer agents View study
Receptor-dependent and receptor-independent endocannabinoid signaling: A therapeutic target for regulation of cancer growth (2013)

Cannabinoids are a class of pharmacological compounds that offer better therapeutic applications as anti-tumor drugs depending on their ability to inhibit the proliferation of tumor cells and survival.This review of recent work provides a general description of the main findings about the effects of endogenous and / or synthetic cannabinoids in breast and prostate cancers. Information is also given on the receptor-independent mechanisms of the anticancer effects of cannabinoids under in vitro and in vivo conditions. View study
Strategies for Improving the Lives of Women Aged 40 and Above Living With HIV/AIDS [Internet] (2016)

The objective of this research was to identify and characterize the empirical studies of strategies for the comprehensive treatment of women over 40 years of age or older living with HIV / AIDS. View study
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (2016)

The medicinal uses of marijuana have been known for a long time. This research aimed to study the conduction to CB2 cannabinoid receptors as a new therapy to treat malignant lymphoblastic disease. In summary, the results presented here show that activation of the CB2 receptor signals apoptosis through a stimulation dependent on the ceramide of the mitochondrial intrinsic pathway View study