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• View All (505)The endocannabinoid system drives neural progenitor proliferation (2005)
The discovery of multipotent neural progenitor (NP) cells has given great support to the existence of neurogenesis in the adult brain. Endocannabinoids, derived from marijuana, act as neuromodulators through CB1 presynaptic receptors and also control the death and survival of neural cells. In this study we show that progenitor cells express a functional endocannabinoid system that actively regulates cell proliferation both in vitro and in vivo. Specifically, the (NP) produce endocannabinoids and express the CB1 receptor and the endocannabinoid inactivating fatty acid hydrolase enzyme (FAAH). View study
The endocannabinoid system in normal and pathological brain ageing (2011)
Aging is associated with a decline in motor coordination, sensory abilities, attention and cognitive performance, which together are responsible for the deficits in learning and memory tasks. This research was based on studying the cellular and molecular mechanisms that underlie the protective effect of the cannabinoid system on brain aging. View study
The endocannabinoid system- a new target for the regulation of energy balance and metabolism (2007)
Now there is solid evidence to support the notion that the endocannabinoid system (EC) has very significant effects.on the energetic balance and the metabolism through the central control of the appetite and by affecting the peripheral metabolism.This research focused on the study of the endocannabinoid system as a new regulator of energy balance and metabolism. View study
The Endocannabinoid System, Cannabinoids, and Pain (2013)
The Endocannabinoid-CB Receptor System: Importance for development and in pediatric disease (2004)
Endogenous cannabinoids (endocannabinoids) and their CB1 and CB2 cannabinoid receptors are present from the early stages of gestation and perform a series of vital functions for the developing organism.The present research was based on studying the endocannabinoid receptor system (CB) as well as defining its importance in the treatment of pediatric diseases. View study
The endogenous cannabinoid system and its role in nociceptive behavior (2004)
In this research, a review was made of recent genetic, behavioral and pharmacological studies that have proven the function of the endocannabinoid system in the sensation of pain. View study
The orphan receptor GPR55 is a novel cannabinoid receptor (2007)
It was possible to conclude through the obtained data that the orphan receiver GPR55.es is a new cannabinoid receptor, and its ligand profile with respect to CB1 and CB2 View study
The role of endogenous cannabinoids in the hypothalamo-pituitary-adrenal axis regulation (2004)
Exogenous cannabinoids affect multiple hormonal systems, including the hypothalamic-pituitary-adrenocortical (HPA) axis. This research focused on evaluating the role of endogenous cannabinoids in axis regulation (HPA) by studying knockout mice for the CB1 (KO) and wild type (WT) receptor. View study
The therapeutic potential of novel cannabinoid receptors (2009)
In this research the therapeutic value of the new cannabinoid receptors will be reviewed, and we will discuss their true belonging to the endocannabinoid signaling system. View study