Epilepsy Medical Cannabis Studies

The current status of artisanal cannabis for the treatment of epilepsy in the United States (2017)

This study presents data on the efficacy and adverse effects of artisanal cannabis in patients with epilepsy in the states of Washington, California and Maine. View study
The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy (2003)

These studies demonstrate the role of the endogenous cannabinoid system in the regulation of seizure activity and the modulation of neuroexitation, which demonstrates the potential of cannabinoids as anticonvulsants. View study
The Pharmacological Basis of Cannabis Therapy for Epilepsy (2016)

Essay on the pharmacological and therapeutic fundamentals of cannabis, with a focus on the endocannabinoid mechanisms underlying the emerging neurotherapeutics of CBD in epilepsy. View study
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome (2017)

In this study, cannabidiol was used to treat seizures in patients with Dravet syndrome, and resulted in a greater reduction in seizure frequency. View study
Understanding Cannabinoids and Epilepsy (-)

Dr. James Bradstreet, an experienced and respected physician in the treatment of autism, epilepsy and associated disorders, indicates that cannabinoids can treat epilepsy. CBD and THC are effective in cases of epilepsy resistant to conventional treatments. View study
Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se (2014)

Cannabidiol is a non-psychoactive cannabinoid, well tolerated and anticonvulsant. Here, we investigate the effects of CBD and the structurally similar cannabinoid cannabigerol (CBG), where CBG had no effect on seizures induced in animal models. View study