Cancer Medical Cannabis Studies

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Cannabis-based medicine for nausea and vomiting in people treated with chemotherapy for cancer (2015)

Conventional anti-cancer drugs do not always work for everyone, and can cause nausea and vomiting. Therefore, therapeutic THC-based drugs (Cannabis) have already been approved for use in some countries. View study
CBD inhibits angiogenesis by multiple mechanisms (2012)

Cannabidiol can inhibit angiogenesis (a physiological process that consists in the formation of new blood vessels from pre-existing vessels) through different mechanisms. Based on the results of this study, it is demonstrated that cannabidiol has the potential to be used as an effective agent in cancer therapy. View study
Ceramide: a new second messenger of cannabinoid action (2001)

Taking into account the emergent role of ceramide in the control of cell fate, in addition to the growing range of functions modulated by cannabinoids, it is possible to say that the cannabinoid-ceramide connection could generate interesting physiological implications and therapeutic possibilities. View study
Clinical Significance of Cannabinoid Receptors CB1 and CB2 Expression in Human Malignant and Benign Thyroid Lesions (2015)

Cannabinoid receptors may be involved in malignant thyroid transformation. These receptors, especially the CB2 receptor, are potential targets in the therapy of thyroid neoplasia. View study
Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach. 2nd edition (2016)

With this update of the consolidated guidelines on the use of antiretroviral drugs to treat and prevent HIV infection, WHO, for the first time, recommends that all people living with HIV receive antiretroviral therapy (ART). In this update We want to provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral drugs (ARV) to treat and prevent HIV infection and the care of people living with HIV. View study
COX-2 and PPAR-g Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells (2012)

These data reveal a new proapoptotic mechanism of cannabidiol that involves the initial positive regulation of cyclooxygenase-2 COX-2 and PPAR-g and a subsequent nuclear translocation of PPAR-g by PG-dependent COX-2. View study
D9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo (2008)

It has been shown that THC (marijuana’s main cannabinoid) potentiates or inhibits tumor growth, depending on the type of cancer and its pathogenesis. These data suggest that THC and other cannabinoids should be explored as new therapeutic molecules for the treatment of certain lung cancers. View study
Differential role of cannabinoids in the pathogenesis of skin cancer ()

In this study conducted in mice, cannaninoids such as ?9-tetrahydrocannabinol (THC) were able to greatly inhibit the tumor growth of melanomas HCmel12 and B16. The results of this study confirm the value of exogenous cannabinoids for the treatment of melanoma, but do not support the role of the endogenous cannabinoid system in the pathogenesis of skin cancer. View study
End of Life Care for Infants, Children and Young People with Life-Limiting Conditions: Planning and Management (2016)

In modern Western society, the family or caregivers do not expect the death of a child, and therefore it has broad and devastating consequences. This guide is directed to all pediatric care providers at the end of life, whatever their level of practice, and also to children and young people with conditions that limit their lives and to their parents or caregivers. View study
Endocannabinoids and fatty acid amides in cancer inflammation and related disorders (2000)

In this study the antitumor and antiinflammatory activity of the endocannabinoids anandamide and 2-araquidonoil glycerol is discussed; the amides of bioactive fatty acids palmitoylethanolamide and oleamide; and some derivatives such as N-acyl vanillyl amines. View study
Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (Review) (06/01/05)

The potential of cannabinoids to delay the growth and spread of cancerous tumors is extraordinary, as it highlights their safety profile in terms of toxicity and can also be used in the treatment of nausea and vomiting in patients with cancer. View study
Endocannabinoids as Guardians of Metastasis (2016)

This study summarizes the complexity of cannabinoid signaling in the area of tumor growth and metastasis. View study