Cancer Medical Cannabis Studies

• View All (505)

Endocannabinoids in endocrine and related tumours (2008)

There is a wide range of pathophysiological conditions that are related to cannabinoids and recently it has been shown that endocannabinoids inhibit or delay cell growth, and the metastasis of tumors of the thyroid, breast and prostate. Which suggests its potential for in the treatment of various types of cancer. View study
Enhancing the Activity of Cannabidiol and Other Cannabinoids In Vitro Through Modifications to Drug Combinations and Treatment Schedules (2013)

It is proven that cannabinoids have numerous therapeutic qualities. In this study the activity of six cannabinoids, used alone and in combination in leukemic cells, was analyzed. View study
Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (2011)

This study shows that canbinoids can help reduce the production of prostaglandins that are important mediators in the inflammatory process. In other words, the anti-inflammatory potential of cannabinoids is demonstrated. View study
Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells (2016)

In this study we investigated the activation of the ER stress pathway after the expression of ectopic hepatitis B virus (HBV) envelope proteins in liver cancer cells, and the role played by the B cannabinoid receptors. The results suggest that HBV envelope proteins can induce the ER stress pathway. The expression of cannabinoid receptors correlates directly with the ER stress function. View study
Expression and Functional Relevance of Cannabinoid Receptor 1 in Hodgkin Lymphoma (2013)

There is evidence that the CB1 cannabinoid receptor is expressed in certain types of malignant tumors. This study identifies the cannabinoid receptor CB1 as a characteristic of Hodgkin’s lymphoma, which could serve as a possible selective target for its treatment. View study
Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: Growth inhibition by receptor activation (2008)

These results suggest that therapies using cannabinoid receptor ligands will be effective in reducing the tumor burden in malignant lymphoma overexpressing CB1 and CB2 receptors. View study
High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma (2003)

This research was done in relation to mantle cell lymphoma (MCL). In order to identify the tumor characteristics that improve the understanding of the biology of MCL, oligonucleotide microarray analyzes were used to define specific gene expression profiles. View study
Id-1 Is a Key Transcriptional Regulator of Glioblastoma Aggressiveness and a Novel Therapeutic Target (2012)

This research showed that the transcriptional regulator Id-1 plays a critical role in the modulation of the invasiveness of glioblastoma cell lines and primary glioblastoma cells. It should be mentioned that the genetic destruction of Id-1 leads to a considerable increase in survival in an orthotopic model of human glioblastoma. The results show that Id-1 regulates multiple pathways of tumor promotion in glioblastoma and that drugs targeting Id-1 represent a new strategy to improve therapy and the outcomes of patients with glioblastoma. View study
Impact of Medical Cannabis on Patient-Reported Symptoms for Patients With Cancer Enrolled in Minnesota's Medical Cannabis Program. (2019)

Minnesota’s medical cannabis program is unique, in that it routinely collects patient-reported scores on symptoms. The objective of this article was to focus on changes in the severity of symptoms reported by cancer patients during the first 4 months of participation in this program. View study
In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma (07/01/05)

The results of this study confirm the antitumourigenic actions of the active compound cannabidiol (cbd) in neuroblastoma cells (nbl), and support its exploitation as an efficient drug in the treatment against cancer (nbl). View study
Increasing Antiproliferative Properties of Endocannabinoids in N1E-115 Neuroblastoma Cells through Inhibition of Their Metabolism (2011)

This research focused on the study of the antiproliferative properties of endocannabinoids in neuroblastoma N1E-115 cells by inhibiting their metabolism. The results found in this study give us clear evidence of targeting the endocannabinoid system to treat cancer. View study
Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (2008)

According to the results of this research, it can be affirmed that cannabinoids can offer a therapeutic option in the treatment of highly invasive cancers. View study